pentobarbital will lower the level or influence of ethotoin by impacting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Keep an eye on.
pentobarbital boosts effects of ifosfamide by impacting hepatic enzyme CYP2B6 metabolism. Use Caution/Check. Coadministration of ifosfamide with CYP2B6 inducers may possibly raise metabolism of ifosfamide to its metabolite. Watch for increased effects/toxicities if put together with CYP2B6 inducers.
pentobarbital will decrease the level or result of fosaprepitant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
Comment: Barbiturates may perhaps boost adverse effects, like respiratory depression, produced by harmful doses of TCAs. With therapeutic doses of TCAs, barbiturates boost metabolism and decrease blood concentrations of TCAs.
pentobarbital will lessen the extent or impact of vinblastine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Mysterious.
Observe Carefully (one)pentobarbital will reduce the extent or influence of mifepristone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. CYP3A4 inducers haven't been researched, coadministration not advised by manufacturer
pentobarbital will minimize the extent or impact of quinidine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
Keep track of Closely (one)pentobarbital will lessen the extent or result of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Observe INR extra commonly if coadministered with inducers of such isoenzymes and alter warfarin dose if wanted.
Contraindicated (1)pentobarbital will decrease the extent or result of elbasvir/grazoprevir by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Keep an eye on Carefully (1)pentobarbital will reduce the extent or effect of gefitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will decrease the level or influence of ondansetron by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use read more Warning/Watch. No dosage adjustment for ondansetron is usually recommended for individuals on these drugs.
pentobarbital will lower the level or outcome of parecoxib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Mysterious.
pentobarbital will decrease the level or impact of voriconazole by impacting hepatic enzyme CYP2C9/ten metabolism. Minimal/Significance Unidentified.